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Anna Axelsson, MD: Results from INHERIT do not 'close the door' on losartan

November 24, 2014

CHICAGO — While results from the INHERIT trial indicate that losartan had no effect on left ventricular mass or other clinical endpoints compared with placebo in patients with hypotrophic cardiomyopathy, the study does not definitively “close the door” on this therapy, Anna Axelsson, MD, said at the American Heart Association Scientific Sessions.

In the single-center, double blind trial, patients with hypotrophic cardiomyopathy were randomly assigned to 100 mg losartan or matching placebo daily. Researchers observed slight decreases in LV mass in both groups, with no significant difference between losartan or placebo.

Multipotent stem cell treatments offer promise in many diseases

November 24, 2014
Regenerative medicine that uses multipotent stem cells holds promising treatment options for many diseases, according to a speaker at the Exponential Medicine conference…
In the Journals

PROTECT AF: LAA closure superior to warfarin in preventing outcomes at 3.8 years

November 24, 2014
New 3.8-year follow-up data from the PROTECT AF trial have shown that left atrial appendage closure met the criteria for superiority vs. warfarin for the prevention of a…
NAFLD associated with high BP, hypertension in children In the Journals

NAFLD associated with high BP, hypertension in children

November 24, 2014
Pediatric patients with nonalcoholic fatty liver disease were more likely to have high blood pressure and persistent high blood pressure compared with children without…
Meeting News Coverage

DEFEAT-HF: Spinal cord stimulation did not benefit patients with HF

November 24, 2014
CHICAGO — Implantation of a spinal cord stimulator was not associated with clinical benefit or improvement in outcomes as a treatment for advanced HF. Douglas P
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Controversial Issues and Challenging Cases

Controversial Issues and Challenging Cases in the New Frontier of Obesity Online Activity

This activity is supported by an educational grant from Eisai Inc.

Obesity has become a world-wide issue of utmost importance as its incidence and prevalence are associated with dramatic…
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New data may yield a 'change in the paradigm' of HF therapy

November 18, 2014
CHICAGO — Further analyses of the PARADIGM-HF trial provide more information on the efficacy of an…
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CME
Managing Acute Ischemic Stroke in the Emergency Department: Two Decades of Progress

Managing Acute Ischemic Stroke in the Emergency Department: Two Decades of Progress

This activity is supported by an educational grant from Genentech.

According to the American Heart Association Heart Disease and Stroke Statistics 2013 Update, approximately 795,000…
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