Cardiology

Top Story

Losartan fails to improve cardiac function, exercise capacity in hypertrophic cardiomyopathy

February 11, 2016

Compared with placebo, losartan had no effect on cardiac function or exercise capacity and failed to slow down the progression of disease in patients with overt hypertrophic cardiomyopathy, according to results of the INHERIT study published in Heart.

Anna Axelsson, MD, of the department of cardiology, The Heart Center, Copenhagen University Hospital Rigshospitalet, Denmark, and colleagues conducted a randomized, double blind, single-center, placebo-controlled study from 2011 to 2014 to assess the efficacy of losartan as a disease modifier in patients with hypertrophic cardiomyopathy. One hundred thirty-three adult patients with overt hypertrophic cardiomyopathy were randomly assigned 100 mg losartan daily (n = 64) or matching placebo (n = 69) for 12 months. Patient compliance was 93% at the end of the study.

Meeting News Coverage

PACUBA: DEB effective for in-stent restenosis in SFA

February 11, 2016
HOLLYWOOD, Fla. — In terms of patency, a drug-eluting balloon was superior to plain old balloon angioplasty in patients with in-stent restenosis in the superficial…
Breaking News

Doctors urge Congress to preserve the 340B Drug Pricing Program

February 11, 2016
Thousands of physicians from American safety-net hospitals signed a letter sent to Congress highlighting the importance of the 340B Drug Pricing Program.The letter asks…
Meeting News CoverageVideo

VIDEO: Lack of high-sensitivity troponin assay availability creates disconnect between guidelines

February 11, 2016
ORLANDO, Fla. — Venugopal Menon, MD, director of the coronary care unit at the Cleveland Clinic and professor of medicine at the Cleveland Clinic Lerner College…
In the Journals

Dementia incidence decreases over time among Framingham Heart Study participants

February 10, 2016
Incidence of dementia significantly decreased over time among participants in the Framingham Heart Study, according to recent findings. “As the average life…
More News Headlines »
morganatic-roan morganatic-roan