Cardiology

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CIRCUS: Cyclosporine before PCI fails to improve outcomes after STEMI

August 30, 2015

LONDON — Intravenous cyclosporine administered before PCI did not improve outcomes or prevent left ventricular remodeling at 1 year compared with placebo in patients with anterior STEMI.

The phase 3, randomized, double blind CIRCUS trial enrolled 970 patients with acute anterior STEMI and complete occlusion of the culprit coronary artery who were referred for PCI within 12 hours of symptom onset at 42 hospitals Belgium, France and Spain. Patients were randomly assigned to receive a bolus injection of cyclosporine (2.5 mg/kg body weight; CicloMulsion, NeuroVive Pharmaceutical) or placebo before coronary recanalization. Seven patients were lost between randomization and 1 year. 

Meeting News Coverage

Age predicts recurrent cerebral ischemia after PFO closure

August 29, 2015
LONDON — Recurrent cerebral ischemia after patent foramen ovale closure is more likely to occur in patients aged 55 years and older, researchers reported at the…
Meeting News Coverage

Joint guideline offers new algorithm for treatment of pulmonary hypertension

August 29, 2015
LONDON — In a new guideline, the European Society of Cardiology and the European Respiratory Society outline a treatment algorithm for pulmonary hypertension and…
Meeting News Coverage

Meta-analysis: LAA occlusion linked with improved outcomes vs. warfarin, aspirin in patients with AF

August 29, 2015
LONDON — Left atrial appendage occlusion was associated with improved mortality and similar stroke outcomes compared with warfarin in patients with atrial…
Meeting News Coverage

New ESC guideline recommends radial approach for PCI in patients with ACS

August 29, 2015
LONDON — A new European Society of Cardiology guideline on management of ACS without persistent ST-segment elevation recommends that PCI performed on patients with…
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CME
Highlights from Lipid Forum 2015™: Focus on Hypertriglyceridemia

Highlights from Lipid Forum 2015®: Focus on Hypertriglyceridemia

This activity is supported by an educational grant from AstraZeneca.

Hypertriglyceridemia is a highly prevalent yet modifiable risk factor for atherosclerotic disease, pancreatitis, and…
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Video
VIDEO: Prenatal intervention may improve neurodevelopmental outcomes from congenital heart defects

VIDEO: Prenatal intervention may improve neurodevelopmental outcomes from congenital heart defects

July 23, 2015
PHILADELPHIA — In this video, J. William Gaynor, MD, a cardiac surgeon at the Children's Hospital of…
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CME
Cardiology Case Consults

The Patient With Idiopathic Pulmonary Fibrosis

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with idiopathic pulmonary fibrosis.
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