Cardiology

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Insufficient evidence to show causal relationship between cystatin C, CVD

August 24, 2016

Mendelian randomization analyses do not suggest a causal relationship between cystatin C and CVD, researchers reported in the Journal of the American College of Cardiology.

Using mendelian randomization analyses, researchers combined data from 76,481 participants from 16 prospective cohorts with 37,126 measures of cystatin C as well as genetic data from 43 studies (n = 252,216) with 63,292 CVD events. The common variant rs911119 in CST3 was used to determine if cystatin C plays a causal role in CVD.

In the Journals

TAVR survival rate similar in patients with aortic stenosis, cancer vs. no cancer

August 23, 2016
Patients with severe aortic stenosis and active cancer who undergo transcatheter aortic valve replacement had comparable survival rates compared with patients with
In the Journals

Personalized approach to statin allocation benefits older patients

August 23, 2016
New data from the BioImage study suggest that personalizing the 2013 American College of Cardiology/American Heart Association guidelines for statin use in older…
In the Journals

Micromesh stent for CAS shows safety and efficacy, low rates of plaque prolapse

August 23, 2016
In patients at various levels of surgical risk undergoing carotid artery stenting, a double-layer micromesh stent appears to be a safe and effective technology, yielding…
In the Journals

History of stroke may increase risk for late-onset Alzheimer’s disease

August 23, 2016
Patients with a history of stroke have double the risk for late-onset Alzheimer’s disease in its familial and sporadic forms, researchers reported in JAMA
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