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VIDEO: Roxana Mehran, MD, discusses REGULATE-PCI results

March 31, 2015

SAN DIEGO — In this video, Roxana Mehran, MD, professor of medicine at Icahn School of Medicine at Mount Sinai and associate medical editor of Cardiology Today's Intervention, highlights results from the REGULATE-PCI study, which she presented at the American College of Cardiology Scientific Sessions.

The trial compared REG1 (Regado Biosciences), a novel anticoagulation system combining pegnivacogin and the reversal agent anivamersen, with bivalirudin among patients undergoing angioplasty. Mehran noted that while the goal was to enroll 13,200 patients, the trial was terminated upon enrollment of approximately 3,200 patients after 10 participants assigned to the REG1 group experienced severe allergic reactions compared with one participant assigned bivalirudin.

BioMed Central retracts 43 articles that used fabricated reviewers

March 31, 2015
Following an investigation which revealed attempts to manipulate the peer review process, medical and scientific publisher BioMed Central has retracted 43 articles that…
Stephen J. Nicholls, MBBS, PhD In the Journals

High-dose statins mitigate association between elevated phospholipids, MACE in patients with stable CAD

March 31, 2015
Elevated oxidized phospholipids on apolipoprotein B-100 predicted secondary major adverse CV events in patients with stable CAD, but the risk was mitigated in those…
In the Journals

Vitamin D supplementation fails to lower BP

March 31, 2015
Vitamin D does not appear to be effective as a means of lowering BP, either in individual patients or as a population-level intervention, according to recent…
Monika Sanghavi, MD In the Journals

Number of births may affect atherosclerosis risk in women

March 31, 2015
The number of live births is associated with subclinical coronary and aortic atherosclerosis in women, according to new data from the Dallas Heart Study.Researchers…
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CME
Debating the Differences and Nuances of Antiplatelet Therapy in ACS and PCI: Not a One-Size-Fits-All?

Debating the Differences and Nuances of Antiplatelet Therapy in ACS and PCI: Not a One-Size-Fits-All?

This activity is supported by an educational grant from Daiichi Sankyo, Inc. and Lilly USA, LLC.

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Meeting News Coverage Video
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Researcher looks at relationship between atopic dermatitis, obesity and cardiovascular disease

March 30, 2015
SAN FRANCISCO — In this video, Jonathan I. Silverberg, MD, PhD, MPH, discusses studies examining cardiovascular…
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CME
Severe Hypertriglyceridemia: Confronting the Complex Issues in Etiology and Treatment

Severe Hypertriglyceridemia: Confronting the Complex Issues in Etiology and Treatment

This activity is supported by an educational grant from AstraZeneca.

Hypertriglyceridemia is a highly prevalent, yet modifiable, risk factor for atherosclerotic disease, pancreatitis, and…
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