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Interferon-alpha led to remission in patients with eosinophilic granulomatosis with polyangiitis

April 26, 2017

Among 30 patients with eosinophilic granulomatosis with polyangiitis, treatment with interferon-alpha led to remission in 25 patients, according to a recently published, observational cohort study.

“The data demonstrated that [interferon-alpha] IFN-α is an effective agent for remission induction and steroid tapering in [eosinophilic granulomatosis with polyangiitis] EGPA, although serious adverse effects may occur,” Benjamin Seeliger, MD, at Jena University Hospital, and colleagues wrote. “Given its beneficial effect on [pulmonary function test] PFT and symptoms, it provides an alternative for standard therapy, especially for patients with persistent asthmatic symptoms and without poor prognostic factors.”

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