Cardiology

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Majority of adverse events in clinical trials remain unpublished

September 30, 2016

A lower number and smaller range of adverse events were reported in published studies compared with those unpublished, according to data published in PLoS Medicine.

“We identified serious concerns about the substantial amount of unpublished adverse events data that may be difficult to access or ‘hidden’ from health care workers and members of the public,” Su Golder, PhD, in the Department of Health Sciences at the University of York in the United Kingdom, and colleagues wrote. “Incomplete reporting of adverse events within published studies was a consistent finding across all the methodological evaluations that we reviewed.”

In the Journals

Proton pump inhibitors increase 2-year MACE risk in patients treated with clopidogrel, PCI

September 30, 2016
In clopidogrel-treated patients who undergo PCI, the use of proton pump inhibitors is associated with significantly higher 2-year adjusted risk for MACE and net adverse…

NIH names Goff director of CV sciences for NHLBI

September 30, 2016
The NIH announced that it has selected David C. Goff, Jr., MD, PhD, as the new director of the NHLBI’s division of cardiovascular sciences.

Novel antihypertensive agent shows positive topline results

September 29, 2016
Quantum Genomics announced that its novel antihypertensive agent was associated with positive topline results in an early study in patients with hypertension. In the…
In the Journals

Allopurinol use reduced risk for myocardial infarction in Medicare beneficiaries

September 29, 2016
Allopurinol use reduced the risk of myocardial infarction in Medicare beneficiaries, according to recently published data. In addition, longer durations of allopurinol…
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Health Care Legislative and Regulatory Update

Pay careful attention regarding evaluation and management services and the global surgery period

September 28, 2016
From international law firm Arnold & Porter LLP comes a timely column that provides views on current regulatory and…
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Meeting News Coverage

VIDEO: Palliative care increasing in prominence for management of patients with HF

September 21, 2016
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Discoveries from ACC 2016: Angina

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