May 30, 2016
SAN FRANCISCO — In patients with persistent atrial fibrillation, the addition of left atrial appendage excision to pulmonary vein isolation did not improve recurrence rate, researchers reported at the Heart Rhythm Society Annual Scientific Sessions.
Researchers randomly assigned 176 patients with persistent AF to video-assisted thoracoscopic surgical ablation with pulmonary vein isolation (PVI) alone or PVI plus additional left atrial appendage (LAA) excision. Freedom from recurrence of AF lasting longer than 30 seconds was the primary endpoint. Secondary endpoints included freedom from any atrial arrhythmia. Follow-up lasted 18 months.