December 1, 2015
Patients undergoing primary PCI for STEMI who present with moderate or severe fatty liver disease were more likely to have impairment of myocardial perfusion compared with patients with less severe disease, according to recent findings.
Researchers sought to determine the effect of nonalcoholic fatty liver disease (NAFLD) on myocardial perfusion and incidence of in-hospital MACE among 186 patients without diabetes (mean age, 58 years; 76% men). All participants had been diagnosed by ultrasound and were treated with PCI within 72 hours of hospital admission. Clinicians used a semiquantitative severity score to classify patients as having mild (score < 3) or moderate-severe (score ≥ 3) NAFLD. They measured myocardial blush grade and used ST-segment resolution analysis to determine myocardial perfusion.