February 27, 2015
SEATTLE — Statin therapy may reduce the volume of non-calcified coronary plaque in patients with HIV and subclinical atherosclerosis, according to data presented here at CROI 2015.
“Numerous epidemiological studies have shown that coronary artery disease is a major cause of morbidity and mortality for patients living with HIV around the world today,” Janet Lo, MD, of the Massachusetts General Hospital and Harvard Medical School, said during an oral presentation. “Within the HIV population, statins have been demonstrated to improve lipids, endothelial function on markers of inflammation, and immune activation, as well as other effects. However, no studies have yet directly assessed the effects of statins on coronary plaque in HIV patients.”