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Botulinum toxin injection during CABG suppresses AF for 1 year

Botulinum toxin injection during CABG suppresses AF for 1 year
May 19, 2015

Read the Perspective from Jonathan M. Kalman, MBBS, FRACP, PhD, FACC, FHRS

BOSTON — Injection of botulinum toxin into epicardial fat pads during CABG reduced the incidence of postoperative atrial fibrillation and suppressed recurrent atrial fibrillation for 1 year, according to findings presented at the Heart Rhythm Society Annual Scientific Sessions.

Researchers randomly assigned 60 patients with paroxysmal AF and an indication for CABG to an injection of botulinum toxin (Xeomin, Merz Pharmaceuticals) 50 U/1 mL at each fat pad or placebo (0.9% normal saline, 1 mL at each fat pad) during surgery.

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