Cardiology Today


The following articles appeared in the print edition of CARDIOLOGY TODAY.

Table of Contents
Cover Story

CVD prevention, treatment challenging as patients with HIV and HCV live longer

FDA News

FDA: Use of TAVR system expanded to include aortic valve-in-valve replacement

FDA grants priority review for investigational HF treatment

New administration option for ticagrelor now approved

FDA approves ivabradine for treatment of HF

FDA approves blood pump system for patients undergoing high-risk PCI

FDA panel backs approval of cangrelor


A tribute to Elijah Saunders, MD

Cardiology Today Editorial Board gathers at ACC 2015

Gene of the Month

Mutations in NR2F2 can induce atrioventricular defects, LV outflow tract obstruction

Robert Roberts, MD, MACC, FRSC, FRCPC

In the Journals

Odds of major bleeding, mortality lower with fondaparinux than heparin

Transcutaneous low-level tragus electrical stimulation suppresses AF

Pre-frailty raises risk for CVD in older adults

Sudden cardiac arrest very low in middle-aged adults during physical activity

High-dose statins mitigate association between elevated phospholipids, MACE in patients with stable CAD

Mood disorders, sex, age linked to inaccurate patient perception of AF burden

Number of donor hearts accepted for transplant declines in US

Number of births may affect atherosclerosis risk in women

HF patients with functional disability at higher risk for hospitalization, early death

LEADLESS published: Lead-free cardiac pacemaker shows good safety, performance at 1 year

Lower-extremity revascularization common, but may be ineffective for nursing home residents with PAD

ED visits for ischemic stroke, TIA declined in past decade

Genetically determined shorter height linked with increased risk for CAD

Consensus statement provides new guidance on minimally invasive valve treatments for children, adults

Expert consensus statement addresses expanding options for percutaneous mechanical support devices

ACP advises against CHD screening in low-risk patients

Industry News

SPYRAL HTN program to evaluate renal denervation for uncontrolled hypertension

Meeting News Coverage

First report of US commercial data for transcatheter mitral valve repair system shows favorable outcomes

Self-expanding TAVR system superior to surgery in high-risk patients at 2 years

CASCADE-FH Registry: Patients lack awareness of familial hypercholesterolemia

Novel anticoagulation system had similar CV outcomes to bivalirudin, linked to increased bleeding, allergic reactions

Ablation superior to amiodarone for treatment of persistent AF in patients with HF

Oral anticoagulants underused for stroke prevention in patients with nonvalvular AF

Excess sedentary time raises risk for coronary artery calcification

Ablation improves rhythm control in mitral valve surgery

EMBRACE-STEMI: Drug targeting mitochondria does not reduce infarct size

IMPROVE-IT: Ezetimibe plus simvastatin reduces total, recurrent CV events

Harrington reflects on past, future of NSTEACS research

Folic acid supplementation reduces stroke risk

ERRICA: Remote ischemic preconditioning fails to improve CABG outcomes

MATRIX: In patients with ACS needing angiography, access site matters but anticoagulant might not

Pharmacology Consult

A look at coagulation assays for target-specific oral anticoagulants

Shreya Patel, PharmD, BCPS; Eyerusalem Befkadu, PharmD candidate

Trial Scorecards

Trial Scorecard: EMBRACE-STEMI

Trial Scorecard: MATRIX

Trial Scorecard: NOTION

Trial Scorecard: ERICCA

Trial Scorecard: BEST

Trial Scorecard: RECESS

Trial Scorecard: OSLER

Trial Scorecard: REVASCAT