• CME
  • Practical Lipidology: Volume 2, Number 1

  • Author(s)/Faculty: Michael Miller, MD, FACC, FAHA; Roger S. Blumenthal, MD, FACC, FCCP, FAHA; Sergio F. Fazio, MD, PhD
    Source: Healio - Cardiology Today Education Lab
    Type: Monograph Articles/Items: 4
    Release Date: 7/1/2012 Expiration Date: 7/1/2013
    Credit Type: CME Number of Credit(s): 1.5
    Cost: Free Provider: Vindico Medical Education
  • For most patients with dyslipidemia, the primary goal of therapy is reduction of low-density lipoprotein cholesterol (LDL-C) levels to a clinically acceptable target. However, achieving this target does not completely eliminate the risk of cardiovascular events. A considerable residual degree of risk remains. The clinician must therefore decide what further goals should be set—further lowering of LDL-C or establishing target levels for other lipid fractions, such as high-density lipoprotein cholesterol (HDL-C), non–HDL-C or triglycerides. These decisions must be reached from the clinical picture presented by the patient together with an assessment of the risk presented by each component of the lipid panel. Finally, the clinician must determine which of the available approaches—lifestyle changes, dietary supplementation or pharmacotherapy with agents such as ezetimibe, niacin, omega-3 acid ethyl esters and fibrates—will be most successful in achieving these goals.

Sponsorship Statement: This continuing education activity is sponsored by Vindico Medical Education.

Support Statement: This activity is supported by an educational grant from .

Target Audience: This program is designed for Cardiologists, Internists, Family Practitioners and other health care professionals in the treatment of patients with hypertriglyceridemia.

Learning Objectives: At the conclusion of this activity participants should be able to:

  1. Describe the contributions of increased non-HDL cholesterol and hypertriglyceridemia as well as low HDL-C to atherosclerosis and coronary heart disease.
  2. Identify current guidelines on non-HDL cholesterol and triglyceride targets for patients at risk for cardiovascular disease.
  3. Evaluate new guidelines for therapeutic lifestyle interventions aimed at reducing triglyceride levels and increasing HDL levels in individuals with borderline-high, high, and very high serum triglycerides.
  4. Discuss the rationale for the use of combination therapies to target elevated non-HDL cholesterol and triglyceride levels.
  5. List options for targeting elevated non-HDL cholesterol and triglyceride levels without adversely affecting other lipid parameters, lowering LDL-C, decreasing markers of inflammation and minimizing drug interactions.

Chief Medical Editor:
Michael H. Davidson, MD, FACC, FACP, FNLA
Editorial Board Member, CHD and Prevention
CARDIOLOGY TODAY
Clinical Professor
Director of Preventive Cardiology
University of Chicago Pritzker School of Medicine
Chicago, IL

Contributing Faculty:
Roger S. Blumenthal, MD, FACC, FCCP, FAHA
Professor of Medicine
Director
Johns Hopkins Ciccarone Center for the Prevention of Heart Disease
Baltimore, MD

Sergio Fazio, MD, PhD
Cornelius Vanderbilt Professor of Medicine and
Professor of Pathology, Immunology and Microbiology
Chief, Section of Cardiovascular Disease Prevention
Vanderbilt University Medical Center
Nashville, TN

Michael Miller, MD, FACC, FAHA
Professor of Medicine, Epidemiology & Public Health
University of Maryland School of Medicine
Director, Center for Preventive Cardiology
University of Maryland Medical Center
Cardiology Division
Baltimore, MD

Accreditation:
Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation:
Vindico Medical Education designates this enduring material activity for a maximum of 1.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, July 1, 2012 to July 1, 2013.

How To Participate in this Activity and Obtain CME Credit:
To participate in this CME activity, you must read the objectives and articles, complete the CME posttest, and complete the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 7 out of 10 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate.

Planning Committee and Faculty:
Roger S. Blumenthal, MD, FACC, FCCP, FAHA
Michael H. Davidson, MD, FACC, FACP, FNLA
Sergio Fazio, MD, PhD
Michael Miller, MD, FACC, FAHA

External Reviewer:
Vera Bittner, MD

Medical Writer:
Steve Pridgeon

Disclosures:
In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control.

The authors disclose that they do have significant financial interests in any products or class of products discussed directly or indirectly in this activity, including research support.

Planning Committee and Faculty members report the following relationship(s):
Roger S. Blumenthal, MD, FACC, FCCP, FAHA
No relevant financial relationships to disclose.

Michael H. Davidson, MD, FACC, FACP, FNLA
Speakers’ Bureau: Abbott, AstraZeneca, GlaxoSmithKline, Merck
Advisory Board/Consultant: Abbott, Aegerion, Amgen, AstraZeneca, Atherotech, Daiichi Sankyo, DTC MD, Esperion, GlaxoSmithKline, iMD (Intelligent Medical Decisions), Kinemed, LipoScience, Merck, NovoNordisk, Roche, sanofi-aventis, Synarc, Takeda, Vindico Medical Education
Grant/Research: Abbott, Daiichi-Sankyo, GlaxoSmithKline, Merck, Roche
Board of Directors: DTC MD, Omthera, Professional Evaluation, Inc. Medical Education Company, Sonogene

Sergio Fazio, MD, PhD
Consulting Fees: Merck, Pfizer, Kowa, Roche, Amarin
Contracted Research: Pfizer, Merck

Michael Miller, MD, FACC, FAHA
Consulting Fees: Abbott, Lupin, Amarin
Fees for Non-CME Services directly from Commerical Interest: Merck
Contracted Research: Abbott, Merck, Roche

External Reviewer reports the following relationship(s):
Vera Bittner, MD
Consulting Fees: Amarin, Kowa, Roche, Pfizer
Contracted Research: GSK, Roche, NIH/Abbott, Gilead
Other: National Coordinator for ALECARDIO trial: Roche/Cleveland Clinic

Medical Writer reports the following relationship(s):
Steve Pridgeon
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relationship(s):
No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage:
The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.

Copyright Statement:
Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2012 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.