Sponsorship Statement: This continuing medical education activity is jointly sponsored by 
and 
Support Statement: This activity is supported by an educational grant from 
Target Audience: The intended audience for this activity is cardiologists and other healthcare professionals involved in the treatment of patients with dyslipidemia.
Learning Objectives: Upon successful completion of this activity, participants will be able to:
- Describe the epidemiology, prevalence, pathophysiology, and genetic basis of familial hypercholesterolemia and its significant contribution to atherosclerosis and coronary heart disease.
- Screen pediatric and adult patients for elevated total cholesterol, lipoprotein (a) and LDL cholesterol levels and perform a thorough family history to risk stratify patients for cardiovascular disease.
- Implement a comprehensive approach to lipid management that incorporates therapeutic interventions that target the various mechanisms that cause hypercholesterolemia.
- Evaluate evidence-based medicine on combinations of lipid-modifying regimens that target multiple lipid risk factors, including lipoprotein (a), apolipoprotein (apo) B, and total LDL particle number.
- Assess the role of apolipoprotein B and lipoprotein (a) in patients with severe familial hypercholesterolemia.
Course Chair:
W. Virgil Brown, MD
Charles Howard Candler Professor Emeritus
Emory University School of Medicine
Atlanta, Georgia
Faculty:
William C. Cromwell, MD, FAHA, FNLA
Chief, Lipoprotein and Metabolic Disorders Institute
Adjunct Associate Professor
Wake Forest University School of Medicine
Diplomate, American Board of Clinical Lipidology
Raleigh, North Carolina
Erik S.G. Stroes, MD, PhD
Professor of Vascular Medicine
Head of the Department Vascular Medicine
Academic Medical Center (AMC)
Amsterdam, Netherlands
Peter P. Toth, MD, PhD
Director of Preventive Cardiology
Sterling Rock Falls Clinic, Ltd.
Clinical Professor
University of Illinois School of Medicine
Chicago, Illinois
External Reviewer:
Michael H. Davidson, MD
Accreditation:
This educational activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Vindico Medical Education and Cardiology Today®. Vindico Medical Education is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation:
Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This enduring material is approved for 1 year from the date of original release, March 29, 2012 to March 28, 2013.
How To Participate in this Activity and Obtain CME Credit:
To participate in this CME activity, you must read the objectives, answer the pretest questions, watch and listen to the presentations, complete the posttest, and complete the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 3 out of 4 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)TM certificate.
Disclosures:
In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control.
The authors disclose that they do have significant financial interests in any products or class of products discussed directly or indirectly in this activity, including research support.
Planning Committee and Faculty members report the following relationship(s):
W. Virgil Brown, MD
Consulting Fees: Abbott, Amgen, Anthera, Atherotech, BMS, Cerenis, Genzyme, Pfizer, Liposcience, Merck, Regeneron
Fees for Non-CME Services: Liposcience, Merck
William C. Cromwell, MD
Consulting Fees: Genzyme, Health Diagnostics Laboratory, Isis, Labcorp
Fees for Non-CME Services: Abbott, Kowa, Liposcience, Merck
Erik S.G. Stroes, MD. PhD
Consulting Fees: Genzyme, ISIS, Santaris, BMS, Enceladus Pharmaceuticals, CSL-Behring Inc, Novartis
Peter P. Toth, MD, PhD
Consulting Fees: Abbott, AstraZeneca, Atherotek, Genentech, Kowa, Merck
Fees for Non-CME Services: Abbott, AstraZeneca, Boehringer-Ingelheim, GlaxoSmithKline, Kowa, Merck, Takeda
External Reviewer reports the following relationship(s):
Michael H. Davidson, MD
Speakers’ Bureau: Abbott, AstraZeneca, GlaxoSmithKline, Merck
Advisory Board/Consultant: Abbott, Aegerion,Amgen, AstraZeneca, Atherotech, Daiichi-Sankyo, DTC MD, Esperion, GlaxoSmithKline, iMD (Intelligent Medical Decisions), Kinemed, LipoScience, Merck, NovoNordisk, Roche, sanofi-aventis, Synarc, Takeda, Vindico Medical Education
Grant/Research: Abbott, Daiichi-Sankyo, GlaxoSmithKline, Merck, Roche
Board of Directors: DTC MD, Omthera, Professioal Evaluation, Inc. Medical Education Company, Sonogene
Vindico Medical Education and Cardiology Today® staff report the following relationship(s):
No relevant financial relationships to disclose.
Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.
Unlabeled and Investigational Usage:
The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.
Copyright Statement:
Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-848-1000; Fax: 856-848-6091. Printed in the USA. Copyright © 2012 SLACK Incorporated®. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education and Cardiology Today® continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education and Cardiology Today®. Neither Vindico Medical Education, Cardiology Today®, nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.