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Januvia may prevent heart disease in HIV patients

May 21, 2015

The antidiabetic drug Januvia demonstrated beneficial systemic and adipose anti-inflammatory effects in HIV-infected adults with impaired glucose tolerance, according to research published in the Journal of Clinical Endocrinology and Metabolism.

“The goal has been to identify treatments that not only address problems with blood sugar and lipids, but also can lower inflammation, which can play a substantial role in heart disease and stroke,” Kevin E. Yarasheski, PhD, professor of medicine at Washington University School of Medicine, said in a press release. “With [Januvia (sitagliptin, Merck)], sugar levels fell, and several markers of immune activation and inflammation were reduced, indicating the drug may provide long-term benefits for these patients’ hearts, bones and livers.”

In the Journals

Diabetes linked to increased CVD mortality risk among Chinese adults

April 29, 2015
An increased risk for death among Chinese adults, especially from cardiovascular disease, is linked to diabetes, according to recent study findings published in…
April Armstrong In the Journals

Diabetic patients with psoriasis may have higher risk of microvascular, macrovascular complications

April 28, 2015
Diabetic patients with psoriasis generally had an increased risk microvascular and macrovascular complications compared with diabetic patients without psoriasis;…
In the Journals

Type 1 diabetes increases post-CABG mortality risk

April 22, 2015
Patients with type 1 diabetes appear to have twice the risk for death after undergoing CABG than patients without type 1 diabetes, according to recent findings.Type 2…
CME
Opening the Window of Time in Stroke Therapy: New Evidence for the Emergency Department

Opening the Window of Time in Stroke Therapy: New Evidence for the Emergency Department

This activity is supported by an educational grant from Genentech, Inc.

The Centers for Disease Control and Prevention report an annual 130,000 stroke-related fatalities in the United States…
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Meeting News Coverage Video
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Francesco Rubino, MD: 'Converting' bariatric surgery into a diabetes intervention poses challenges

October 24, 2014
BOSTON — Converting a procedure that has been used for years as a weight-loss intervention into a treatment aimed…
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CME
Cardiology Case Consults

The Patient with Familial Hypercholesterolemia

This CME activity will focus on the diagnosis and management of patients with familial hypercholesterolemia.
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AHA and ADA: CV risk assessment, monitoring essential for patients with type 1 diabetes

August 21, 2014
A greater understanding of the pathophysiology, risk prediction and treatment of CVD in patients with type 1 diabetes is essential to minimize the…
Steven E. Nissen, MD, MACC FDA News

FDA opens dialogue on interim results of CV safety in diabetes drug trials

August 12, 2014
The FDA has launched a dialogue on how to handle confidentiality of the interim results for cardiovascular outcomes in diabetes treatment trials…
In the Journals

Knowing modifiable risk factors may reduce CV death in type 2 diabetes

July 9, 2014
Determining vascular calcification and modifiable risk factors for heart disease could provide patients with type 2 diabetes the insight needed to…
Meeting News Coverage

Higher obesity increases odds for cardiovascular, cancer, diabetes deaths

July 8, 2014
Adults with class III obesity are more likely to die from all causes than those within normal weight range, but particularly from heart disease…
In the JournalsPerspective

'Bundled' management reduced diabetes-related vascular complications

July 3, 2014
A team-based model with an all-or-none or “bundled” approach to primary care reduced the risk for myocardial infarction, stroke and…
In the Journals

Sitagliptin may increase hospitalizations in patients with diabetes, HF

July 2, 2014
Recent study results found that sitagliptin use by patients with type 2 diabetes and HF may increase the risk for HF-related…
In the Journals

CV risk control differs by sex for patients with type 2 diabetes

July 2, 2014
Composite control of cardiovascular risk factors varies by sex for patients with type 2 diabetes, with women’s significantly lower than…
Meeting News Coverage

RYGB adds CV, quality-of-life benefits for obesity, type 2 diabetes

July 1, 2014
CHICAGO — Roux-en-Y gastric bypass surgery could bring additional benefits for some patients with obesity and type 2 diabetes, according to…
In the Journals

Homeless men boosted health playing pick-up soccer

June 29, 2014
As World Cup competition continues, a timely study published in the Scandinavian Journal of Medicine & Science in Sports showed that playing…
In the Journals

CABG, newer-generation DES yielded similar mortality rates in patients with diabetes

June 26, 2014
Comparable mortality rates were reported for patients with diabetes treated with CABG or PCI using a cobalt-chromium everolimus-eluting…
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