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Genetic variant reduces coronary events, increases diabetes risk in familial hypercholesterolemia

June 30, 2015

CHICAGO — A PCSK9 loss-of-function genetic variant was associated with a cardioprotective effect, but increased prevalence of diabetes and prediabetes in patients with familial hypercholesterolemia, according to results presented at the National Lipid Association Scientific Sessions.

Researchers performed genotyping in 724 patients with familial hypercholesterolemia and established the presence of the PCSK9 InsLEU genetic variant to determine its potential link to diabetes, glucose homeostasis and coronary events.

In the Journals

Preventable risk factors related to half of CV deaths in US adults

June 30, 2015
Preventable risk factors accounted for half of CV deaths in U.S. adults aged 45 to 79 years from 2009 to 2010, according to an analysis published in the Annals of
VIDEO: Expert discusses relationship between statin therapy, diabetes Meeting News CoverageVideo

VIDEO: Expert discusses relationship between statin therapy, diabetes

June 12, 2015
CHICAGO — Health care professionals should be aware of the link between statin use and increased risk for type 2 diabetes, especially among patients with risk…
Rury Holman Meeting News CoveragePerspective

No additional threat of heart failure with Januvia in high-risk adults with type 2 diabetes

June 8, 2015
BOSTON – The DPP-IV inhibitor Januvia does not increase cardiovascular risk or benefit in adults with type 2 diabetes at high risk for acute cardiovascular events…
CME
Oral Antiplatelet Therapy in a Patient with Acute Coronary Syndrome and Percutaneous Coronary Intervention

Case Study: Oral Antiplatelet Therapy in a Patient with ACS and PCI

This activity is supported by an educational grant from Daiichi Sankyo, Inc. and Lilly USA, LLC

It is estimated that in the United States, over 780,000 persons annually will experience an acute coronary syndrome…
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Meeting News Coverage Video
VIDEO: Best CV disease treatment approach for patients with diabetes still unclear

VIDEO: Best CV disease treatment approach for patients with diabetes still unclear

May 31, 2015
SAN DIEGO — Spencer King, III, MD, MACC, of the cardiology department at Emory Saint Joseph’s Hospital and…
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CME
PCI in ACS: Deciding Among Clopidogrel, Prasugrel, or Ticagrelor

PCI in ACS: Deciding Among Clopidogrel, Prasugrel, or Ticagrelor

This activity is supported by an educational grant from Daiichi Sankyo, Inc. and Lilly USA, LLC

It is estimated that in the United States, each year, over 780,000 persons will experience an acute coronary syndrome…
More »
In the Journals

Higher insulin dosage for type 2 diabetes may increase mortality risk

December 10, 2014
Patients with type 2 diabetes taking exogenous insulin could be at increased risk for death from all causes, major adverse cardiovascular events and…
Steven Grover In the Journals

Life expectancy, healthy years likely to diminish with obesity-related diabetes, CVD

December 4, 2014
Obesity could reduce life expectancy by up to 8 years and healthy years of life by up to 19 years due to the effects of type 2 diabetes and…
Philipp Blanke Meeting News Coverage

Mild CAD increased CV event risk in patients with diabetes

December 3, 2014
Patients with diabetes who have even mild coronary artery disease are as likely to experience a cardiovascular event as those with serious…
Joseph Muhlestein, MD Meeting News CoveragePerspective

FACTOR-64: CCTA screening for CAD failed to reduce 4-year events in diabetes patients

November 17, 2014
CHICAGO — Screening for CAD by coronary computed tomography angiography did not reduce the composite rate of all-cause mortality, nonfatal MI…
Mohammed Ali In the Journals

'Cascade-of-care' displays gaps in US diabetes diagnosis, treatment

November 17, 2014
Using a cascade model to visualize the gaps in awareness of diabetes diagnosis, engagement in care and treatment in the United States, researchers…
Meeting News Coverage

DCB shows promise in femoropopliteal arterial disease, diabetes

November 6, 2014
A drug-coated balloon was safe and effective at 12 months in patients with femoropopliteal arterial disease and diabetes, according to findings…
Healio CMHC2014 Ferdinand2 th Meeting News CoverageVideo

Keith C. Ferdinand, MD, highlights recent data on link between CVDs, diabetes drugs

October 30, 2014
BOSTON — At the Cardiometabolic Health Congress, Keith C. Ferdinand, MD, FACC, professor of clinical medicine at Tulane University School of…
thumbnail for video 3857626096001 Meeting News CoverageVideo

Francesco Rubino, MD: 'Converting' bariatric surgery into a diabetes intervention poses challenges

October 24, 2014
BOSTON — Converting a procedure that has been used for years as a weight-loss intervention into a treatment aimed primarily at diabetes or…
Keith C. Ferdinand Meeting News Coverage

Cardiometabolic Health Congress highlights latest research on CVD, diabetes, obesity

October 23, 2014
BOSTON — The latest innovative research in diabetes, hypertension, lipids, obesity and thrombosis was analyzed by experts at the…
In the Journals

Atherosclerosis risk increased among men with diabetes, low testosterone

October 17, 2014
A greater risk for developing atherosclerosis is found among middle-aged men with low testosterone and type 2 diabetes, according to recent study…
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