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FACTOR-64: CCTA screening for CAD failed to reduce 4-year events in diabetes patients

November 17, 2014

Read the Perspective from David C. Goff Jr., MD, PhD

CHICAGO — Screening for CAD by coronary computed tomography angiography did not reduce the composite rate of all-cause mortality, nonfatal MI or hospitalization for unstable angina at 4 years in asymptomatic patients with diabetes, despite use of coronary interventions and favorable trends in lipids and BP.

Prior attempts at screening for asymptomatic CAD had been limited to noninvasive tests with variable sensitivity and specificity that were capable of identifying only obstructive CAD causing myocardial ischemia, according to Joseph B. Muhlestein, MD, from Intermountain Medical Center Heart Institute in Murray, Utah, and University of Utah School of Medicine.

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