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ATMOSPHERE: Aliskiren fails to benefit patients with HF, diabetes vs. enalapril

May 26, 2016

In patients with diabetes and HF, the direct renin inhibitor aliskiren did not significantly improve outcomes compared with the ACE inhibitor enalapril, according to new data from the ATMOSPHERE trial.

In the overall results, presented in April, aliskiren (Tekturna, Novartis) alone or combined with enalapril did not improve CV mortality or hospitalization for HF compared with enalapril alone.

Meeting News Coverage

Insulin resistance a culprit for non-alcoholic fatty liver disease

May 21, 2016
NEW ORLEANS — The prevalence of nonalcoholic fatty liver disease is high in patients with diabetes, and insulin resistance is a common cause, according to a…
Meeting News Coverage

Despite guideline changes, statin use unchanged or lower in patients with diabetes

May 21, 2016
NEW ORLEANS — The rate of statin use in adults with diabetes has remained steady or declined since 2014, according to findings presented at the National Lipid…
Trial Scorecards

Trial Scorecard: STAMPEDE

Cardiology Today, May 2016
Researchers compared outcomes of intensive medical therapy, Roux-en-Y gastric bypass surgery or sleeve gastrectomy in patients with mild to moderate obesity and type 2…
In the Journals

Pre-pregnancy cardiac dysfunction may identify risk for recurrent preeclampsia, future CVD

February 29, 2016
Evidence of diastolic and systolic dysfunction and elevated total vascular resistance in the nonpregnant state may predict a woman’s risk for…

In the Journals

Aggressive antihypertensive treatment may cause harm in people with diabetes

February 26, 2016
People with diabetes and systolic blood pressure levels less than 140 mm Hg have an increased risk for death from cardiovascular causes when they are…


The Patient with Heart Failure

February 15, 2016 Expires: 2/15/2017
Over 5 million people in the United States (US) over the age of 20 years have heart failure (HF) and the prevalence of HF is expected to increase…

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Meeting News Coverage

LIBERTY 360° demographic analysis: Diabetes, renal disease, race correlate with PAD severity

February 15, 2016
HOLLYWOOD, Fla. — An interim demographic analysis of the LIBERTY 360° study population of patients with peripheral artery disease indicates…

In the Journals

Repatha shows promise for LDL reduction in type 2 diabetes

February 15, 2016
Adults with type 2 diabetes randomly assigned the PCSK9 inhibitor Repatha saw a 60% reduction in LDL cholesterol during 12 weeks vs. those assigned…

In the Journals

Efforts to improve CHD risk-factor control may reduce racial, ethnic disparities

February 12, 2016
In a study of more than 1.3 million patients in the Kaiser Permanente Health System in Northern California, Asian, black and Hispanic adults had…

In the Journals

Report offers additional tools to determine heart disease risk, treatment in type 2 diabetes

February 6, 2016
The risk for coronary heart disease in patients with type 2 diabetes is lower than previously believed; however, proper risk assessment and…

In the Journals

Intervention program reduces CVD risk in Appalachian patients with diabetes

February 2, 2016
Community lifestyle intervention classes through the Complete Health Improvement Program reduced CVD risk factors in patients with elevated fasting…

In the Journals

CV risk factors increase mortality in patients with dementia

February 1, 2016
CHD, congestive HF, diabetes, male sex and smoking may increase the risk for death in older adults with dementia. Irene E. van de

In the Journals

Long-term niacin therapy may raise risk for new-onset diabetes

January 28, 2016
Results of recent meta-analysis suggest a moderately increased risk for new-onset diabetes after treatment with niacin, regardless of background…

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