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Januvia may prevent heart disease in HIV patients

May 21, 2015

The antidiabetic drug Januvia demonstrated beneficial systemic and adipose anti-inflammatory effects in HIV-infected adults with impaired glucose tolerance, according to research published in the Journal of Clinical Endocrinology and Metabolism.

“The goal has been to identify treatments that not only address problems with blood sugar and lipids, but also can lower inflammation, which can play a substantial role in heart disease and stroke,” Kevin E. Yarasheski, PhD, professor of medicine at Washington University School of Medicine, said in a press release. “With [Januvia (sitagliptin, Merck)], sugar levels fell, and several markers of immune activation and inflammation were reduced, indicating the drug may provide long-term benefits for these patients’ hearts, bones and livers.”

In the Journals

Diabetes linked to increased CVD mortality risk among Chinese adults

April 29, 2015
An increased risk for death among Chinese adults, especially from cardiovascular disease, is linked to diabetes, according to recent study findings published in…
April Armstrong In the Journals

Diabetic patients with psoriasis may have higher risk of microvascular, macrovascular complications

April 28, 2015
Diabetic patients with psoriasis generally had an increased risk microvascular and macrovascular complications compared with diabetic patients without psoriasis;…
In the Journals

Type 1 diabetes increases post-CABG mortality risk

April 22, 2015
Patients with type 1 diabetes appear to have twice the risk for death after undergoing CABG than patients without type 1 diabetes, according to recent findings.Type 2…
CME
Opening the Window of Time in Stroke Therapy: New Evidence for the Emergency Department

Opening the Window of Time in Stroke Therapy: New Evidence for the Emergency Department

This activity is supported by an educational grant from Genentech, Inc.

The Centers for Disease Control and Prevention report an annual 130,000 stroke-related fatalities in the United States…
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Meeting News Coverage Video
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Francesco Rubino, MD: 'Converting' bariatric surgery into a diabetes intervention poses challenges

October 24, 2014
BOSTON — Converting a procedure that has been used for years as a weight-loss intervention into a treatment aimed…
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CME
Cardiology Case Consults

The Patient with Familial Hypercholesterolemia

This CME activity will focus on the diagnosis and management of patients with familial hypercholesterolemia.
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In the Journals

Updated diabetes care guidelines for PCPs stress importance of individualized treatment

March 23, 2015
Recent updates to the American Diabetes Association’s Standards of Medical Care in Diabetes place an emphasis on individualizing and tailoring…
In the Journals

Diabetes prevalence lower in patients with familial hypercholesterolemia than unaffected relatives

March 11, 2015
Patients with familial hypercholesterolemia had a lower prevalence of type 2 diabetes compared with relatives without familial hypercholesterolemia…
Gabriela Vazquez-Benitez In the Journals

Diabetes, CVD increase rates of CV events

February 27, 2015
Among adults with diabetes, paying extra attention to traditional cardiovascular risk factors could reduce the rates of cardiovascular events and…
Jill Kanaley In the Journals

After-dinner exercise decreases CVD risk in type 2 diabetes

February 19, 2015
Cardiovascular disease risk decreased among obese adults with type 2 diabetes when they exercised after a meal, according to study findings published…
In the Journals

BP reduction in type 2 diabetes may lower CVD risks at levels below guideline recommendations

February 10, 2015
A lower risk for cardiovascular disease and coronary heart disease events, as well as improved mortality, was found among patients with type 2…
In the Journals

Immigration variables, not language barriers, affect diabetes complications

February 6, 2015
Language barriers do not appear to increase the risk for diabetes complications in a heterogeneous immigrant population with universal health…
Rachel Simmons In the Journals

CV risk in women with type 1 diabetes nearly double that in men

February 6, 2015
Women with type 1 diabetes have approximately 40% greater risk for death from all causes, and two times the risk for fatal and nonfatal vascular…
Benjamin Scirica In the Journals

Safety of Onglyza unaltered by kidney function

February 4, 2015
Onglyza treatment did not alter the risk for ischemic cardiovascular events in patients with type 2 diabetes who had a range of impaired renal…
Heart Health: New Guidelines and Improvements

Heart Health: New Guidelines and Improvements

February 9, 2015 Expires: 2/10/2016
Heart disease is the leading cause of death in the United States for men and women, claiming approximately 1 million lives each year. This…
In the Journals

Elevated blood glucose linked to early death, other events in patients with acute HF

January 8, 2015
Slight elevation in blood glucose was associated with early mortality, future diabetes and future hospitalization among patients with acute HF, even…
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