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Genetic variant reduces coronary events, increases diabetes risk in familial hypercholesterolemia

June 30, 2015

CHICAGO — A PCSK9 loss-of-function genetic variant was associated with a cardioprotective effect, but increased prevalence of diabetes and prediabetes in patients with familial hypercholesterolemia, according to results presented at the National Lipid Association Scientific Sessions.

Researchers performed genotyping in 724 patients with familial hypercholesterolemia and established the presence of the PCSK9 InsLEU genetic variant to determine its potential link to diabetes, glucose homeostasis and coronary events.

In the Journals

Preventable risk factors related to half of CV deaths in US adults

June 30, 2015
Preventable risk factors accounted for half of CV deaths in U.S. adults aged 45 to 79 years from 2009 to 2010, according to an analysis published in the Annals of
VIDEO: Expert discusses relationship between statin therapy, diabetes Meeting News CoverageVideo

VIDEO: Expert discusses relationship between statin therapy, diabetes

June 12, 2015
CHICAGO — Health care professionals should be aware of the link between statin use and increased risk for type 2 diabetes, especially among patients with risk…
Rury Holman Meeting News CoveragePerspective

No additional threat of heart failure with Januvia in high-risk adults with type 2 diabetes

June 8, 2015
BOSTON – The DPP-IV inhibitor Januvia does not increase cardiovascular risk or benefit in adults with type 2 diabetes at high risk for acute cardiovascular events…
CME
PCI in ACS: Deciding Among Clopidogrel, Prasugrel, or Ticagrelor

PCI in ACS: Deciding Among Clopidogrel, Prasugrel, or Ticagrelor

This activity is supported by an educational grant from Daiichi Sankyo, Inc. and Lilly USA, LLC

It is estimated that in the United States, each year, over 780,000 persons will experience an acute coronary syndrome…
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Meeting News Coverage Video
VIDEO: Best CV disease treatment approach for patients with diabetes still unclear

VIDEO: Best CV disease treatment approach for patients with diabetes still unclear

May 31, 2015
SAN DIEGO — Spencer King, III, MD, MACC, of the cardiology department at Emory Saint Joseph’s Hospital and…
More »
Antiplatelet Therapy in ACS and PCI

Antiplatelet Therapy in ACS and PCI

This activity is supported by an educational grant from Daiichi Sankyo, Inc. and Lilly USA, LLC.

It is estimated that in the United States, each year, over 780,000 persons will experience an acute coronary syndrome…
More »
Meeting News Coverage

Genetic variant reduces coronary events, increases diabetes risk in familial hypercholesterolemia

June 30, 2015
CHICAGO — A PCSK9 loss-of-function genetic variant was associated with a cardioprotective effect, but increased prevalence of diabetes and…
In the Journals

Preventable risk factors related to half of CV deaths in US adults

June 30, 2015
Preventable risk factors accounted for half of CV deaths in U.S. adults aged 45 to 79 years from 2009 to 2010, according to an analysis published in…
VIDEO: Expert discusses relationship between statin therapy, diabetes Meeting News CoverageVideo

VIDEO: Expert discusses relationship between statin therapy, diabetes

June 12, 2015
CHICAGO — Health care professionals should be aware of the link between statin use and increased risk for type 2 diabetes, especially among…
Rury Holman Meeting News CoveragePerspective

No additional threat of heart failure with Januvia in high-risk adults with type 2 diabetes

June 8, 2015
BOSTON – The DPP-IV inhibitor Januvia does not increase cardiovascular risk or benefit in adults with type 2 diabetes at high risk for acute…
Matthew Riddle Meeting News Coverage

Lyxumia trial shows neutral CV risk in adults with type 2 diabetes, high risk for CVD

June 8, 2015
BOSTON — The GLP-1 receptor agonist Lyxumia lowers HbA1c without any cardiovascular risk or benefit in adults with type 2 diabetes at high risk…
Ingrid Gause-Nilsson Meeting News Coverage

No new danger for CV events with Farxiga in older adults

June 6, 2015
BOSTON — Farxiga is not associated with an added risk for cardiovascular events in older adults with type 2 diabetes, cardiovascular disease…
In the Journals

Statins underused in patients with diabetes, noncoronary atherosclerosis

June 3, 2015
Statin use is lower and less aggressive among patients with diabetes and noncoronary atherosclerotic vascular disease compared with those with…
VIDEO: Best CV disease treatment approach for patients with diabetes still unclear Meeting News CoverageVideo

VIDEO: Best CV disease treatment approach for patients with diabetes still unclear

May 31, 2015
SAN DIEGO — Spencer King, III, MD, MACC, of the cardiology department at Emory Saint Joseph’s Hospital and Emory University School of…
In the Journals

Diabetes linked to increased CVD mortality risk among Chinese adults

April 29, 2015
An increased risk for death among Chinese adults, especially from cardiovascular disease, is linked to diabetes, according to recent study findings…
April Armstrong In the Journals

Diabetic patients with psoriasis may have higher risk of microvascular, macrovascular complications

April 28, 2015
Diabetic patients with psoriasis generally had an increased risk microvascular and macrovascular complications compared with diabetic patients…
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