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STAMPEDE: Sustained glycemic benefit observed 5 years after gastric bypass in type 2 diabetes, obesity

STAMPEDE: Sustained glycemic benefit observed 5 years after gastric bypass in type 2 diabetes, obesity
February 21, 2017

Patients with type 2 diabetes and mild to moderate obesity who underwent Roux-en-Y gastric bypass or sleeve gastrectomy saw sustained improvements in HbA1c, body weight, lipid levels and quality of life 5 years after surgery that were superior to medical therapy alone, according to results from the STAMPEDE trial.

“Five years is a long time for follow-up, and that is one of the distinguishing features of this study,” Sangeeta Kashyap, MD, of the department of endocrinology, diabetes and metabolism at Cleveland Clinic, told Endocrine Today. “What is remarkable is patients who underwent bariatric surgery had far better glycemic control, with less use of insulin and medications. Almost 90% of patients did not need insulin after surgery. These patients had better triglycerides, higher HDL cholesterol levels, lower C-reactive protein levels, and maintained almost 20% total body weight loss. And, overall, based on their self-reported questionnaires, they had better quality of life.”

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In the Journals Plus

STAMPEDE: Sustained glycemic benefit observed 5 years after gastric bypass in type 2 diabetes, obesity

February 21, 2017
Patients with type 2 diabetes and mild to moderate obesity who underwent Roux-en-Y gastric bypass or sleeve gastrectomy saw sustained improvements in…

In the Journals

Benefits of statin therapy outweigh diabetes risk

February 20, 2017
In a commentary published in The American Journal of Medicine, experts wrote that the CV benefits of statins outweigh any diabetes-related risk they…

In the Journals

DAPT, aspirin monotherapy confer similar outcomes in patients with diabetes after CABG

February 17, 2017
New data suggest that use of dual antiplatelet therapy may not be clinically warranted in patients with diabetes post-CABG. According to data…

In the Journals

Low socioeconomic status as significant a risk factor for mortality as diabetes, high blood pressure, obesity

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To reduce the risk of mortality, local and global health policies should include efforts to address low socioeconomic status as a contributor to

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