College of Cardiology 59th Annual Scientific Sessions
ATLANTA – Using data from a 10-year Denmark registry of more than
40,000 patients, researchers concluded that psoriasis is a risk factor for
AF, stroke, MI, angioplasty and cardiac
death, according to data released here on Saturday.
“Our results establish psoriasis as a clinically significant and
independent risk factor for a range of CV events,” Ole
Ahleoff, MD, of Copenhagen University Hospital Gentofte, Denmark, said in a
The registry tracked hospital visits and prescriptions of 40,252
adolescent and adult patients with mild-to-severe psoriasis for more than 10
years (1997 to 2006). According to the release, researchers believed there was
a link between psoriasis and CV events because both have severe, associated
The researchers reported that psoriasis was associated with increased
risk for AF in mild symptoms (RR=1.22) and moderate-to-severe symptoms
(RR=1.51). Also, psoriasis was associated with increased risk for stroke in
mild symptoms (RR=1.19) and moderate-to-severe symptoms (RR=1.45).
Patients with moderate-to-severe symptoms who were aged younger than 50
years at the study start had increased risk for AF (RR=2.28) and stroke
(RR=1.92). Patients with moderate-to-severe symptoms also had increased risk
for MI (RR=1.24) vs. those patients with mild symptoms (RR=1.10), according to
Moreover, mild symptoms (RR=1.29) and moderate-to-severe symptoms
(RR=1.59) increased the risk for angioplasty.
“I believe our results call for increased awareness of psoriasis as
a contributor to CVD and for a discussion of future medical management,”
Ahlehoff said in the release.
The Copenhagen University Hospital Department of Cardiology funded this
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