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STAMPEDE: Sustained glycemic benefit observed 5 years after gastric bypass in type 2 diabetes, obesity

STAMPEDE: Sustained glycemic benefit observed 5 years after gastric bypass in type 2 diabetes, obesity
February 21, 2017

Patients with type 2 diabetes and mild to moderate obesity who underwent Roux-en-Y gastric bypass or sleeve gastrectomy saw sustained improvements in HbA1c, body weight, lipid levels and quality of life 5 years after surgery that were superior to medical therapy alone, according to results from the STAMPEDE trial.

“Five years is a long time for follow-up, and that is one of the distinguishing features of this study,” Sangeeta Kashyap, MD, of the department of endocrinology, diabetes and metabolism at Cleveland Clinic, told Endocrine Today. “What is remarkable is patients who underwent bariatric surgery had far better glycemic control, with less use of insulin and medications. Almost 90% of patients did not need insulin after surgery. These patients had better triglycerides, higher HDL cholesterol levels, lower C-reactive protein levels, and maintained almost 20% total body weight loss. And, overall, based on their self-reported questionnaires, they had better quality of life.”

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In the Journals Plus

STAMPEDE: Sustained glycemic benefit observed 5 years after gastric bypass in type 2 diabetes, obesity

February 21, 2017
Patients with type 2 diabetes and mild to moderate obesity who underwent Roux-en-Y gastric bypass or sleeve gastrectomy saw sustained improvements in…

In the Journals

Increase in noncalcified plaque associated with testosterone treatment in older men

February 21, 2017
Testosterone treatment in older men was linked to a significantly greater increase in coronary artery noncalcified plaque volume, according to a new…

In the Journals

Anti-Müllerian hormone trajectories associated with CVD

February 21, 2017
Decline in anti-Müllerian hormone was associated with increased risk for CVD, according to recently published findings. Recent studies had…

In the Journals

High OxPL-apoB levels linked to recurrent stroke, first major coronary events

February 20, 2017
Elevated oxidized phospholipids on apolipoprotein B-100 levels are an indicator of recurrent stroke and first major coronary events in patients who…

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