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MR CLEAN: Nongeneral anesthesia may lead to better outcomes after intra-arterial treatment

February 27, 2015

Read the Perspective from Bruce Ovbiagele, MD, MSc, MAS

NASHVILLE, Tenn. — Among patients randomly assigned to intra-arterial treatment in the MR CLEAN trial, use of nongeneral anesthesia during the procedure was associated with better outcomes compared with use of general anesthesia, according to findings presented at the International Stroke Conference.

The phase 3, multicenter, open-label MR CLEAN study enrolled patients with acute ischemic stroke caused by an intracranial occlusion in the anterior circulation artery; 217 underwent intra-arterial treatment after randomization. Previously published results demonstrated that the treatment group had better results for all outcomes compared with controls.

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