March 6, 2015
SEATTLE — Smoking rates appeared high among men who have sex with men with HIV and were associated with subclinical coronary atherosclerosis, according to data presented at CROI 2015.
Sean Kelly, MD, of the infectious disease department at Northwestern University Feinberg School of Medicine, and colleagues examined the coronary artery calcium (CAC) of 1,005 MSM enrolled in the Multicenter AIDS Cohort Study, including 612 infected with HIV. Participants semiannually self-reported recreational substance use up to 10 years prior, including tobacco, alcohol, stimulants, marijuana, inhaled nitrites and erectile dysfunction medication. CAC was measured in all patients through noncontrast computed tomography, with coronary CT angiograms (n = 764) also performed. Prevalence was determined through regression models stratified by HIV serostatus adjusted for age, race, education, CVD risk factors and HIV clinical factors.