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Bococizumab reduces LDL in patients with hypercholesterolemia

Bococizumab reduces LDL in patients with hypercholesterolemia
April 24, 2015

Use of the PCSK9 monoclonal antibody bococizumab in patients with hypercholesterolemia was associated with significant reductions in LDL across all doses studies, despite dose reductions in many patients.

Researchers reported results from a phase 2b, multicenter, double blind, placebo-controlled, dose-ranging trial of 351 adults with hypercholesterolemia (baseline fasting LDL, ≥ 80 mg/dL; triglycerides, ≤ 400 mg/dL; no incidence of CV events within past 6 months).

At IssuePerspective

When to anticoagulate up for debate with stroke risk scores but no defined thresholds

April 24, 2015
Cardiology Today asked experts in the field to share their views on anticoagulation for patients with atrial fibrillation based on stroke risk stratification scores…
In the Journals

Analysis: IABP more cost-effective than routine use of percutaneous VADs

April 24, 2015
In high-risk patients undergoing primary PCI, use of percutaneous ventricular assist devices was not associated with improved clinical outcomes, reduced length of stay…
Meeting News Coverage

ENDURANCE: Stroke-free survival similar with centrifugal-flow VAD, LVAD

April 24, 2015
Patients with advanced HF ineligible for heart transplantation who were implanted with a centrifugal-flow ventricular assist device system or an axial-flow left…
In the Journals

Pediatric cardiac surgery mortality rate declines in UK

April 23, 2015
From 2000 to 2010, the number of pediatric cardiac surgery procedures performed in the United Kingdom increased, but rates of 30-day mortality have declined, according…
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CME
Severe Hypertriglyceridemia: Confronting the Complex Issues in Etiology and Treatment

Severe Hypertriglyceridemia: Confronting the Complex Issues in Etiology and Treatment

This activity is supported by an educational grant from AstraZeneca.

Hypertriglyceridemia is a highly prevalent, yet modifiable, risk factor for atherosclerotic disease, pancreatitis, and…
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Meeting News Coverage Video
VIDEO: PROMISE results on functional tests, CTA allow clinicians to feel 'comfortable' with resources

VIDEO: PROMISE results on functional tests, CTA allow clinicians to feel 'comfortable' with resources

April 19, 2015
SAN DIEGO — Paul L. Douglass, MD, chief of cardiology at the Atlanta Medical Center, Atlanta, Ga…
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CME
Obesity Consults: Volume 2, Number 4 Obesity and the Cardiovascular System

Obesity Consults: Volume 2, Number 4
Obesity and the Cardiovascular System

This activity is supported by an educational grant from Eisai, Inc. and Vivus, Inc.

Obesity is associated with a wide range of comorbid conditions, including diabetes, hypertension, sleep apnea, and…
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