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Novel apolipoprotein A-I formulation studied in AEGIS-I

November 22, 2014

A new phase 2b trial will assess a novel apolipoprotein A-I formulation and its effect on markers of reverse cholesterol transport and the stabilization of atherosclerotic lesions, according to a press release.

The randomized, placebo-controlled, dose-ranging AEGIS-I study is designed to evaluate the safety and tolerability of multiple weekly infusions of CSL112 (CSL Limited) in a cohort of 1,200 patients with acute MI.

In the Journals

EPA with statins may reduce periprocedural MI in PCI

November 21, 2014
Patients receiving eicosapentaenoic acid with statins before PCI experienced reduced type IVa MI compared with those receiving statins only, recent findings…
In the Journals

CDC: Overall heart disease death rate fell, increased in certain subtypes

November 21, 2014
In a letter published in JAMA, researchers from the CDC reported that mortality rates for heart disease overall have declined, but increases were seen in certain…
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VIDEO: Satellite-based ECG system may improve outcomes for patients with STEMI

November 21, 2014
CHICAGO — Srihari S. Naidu, MD, director of the cardiac catheterization lab at Winthrow University Hospital in Mineola, New York, provides perspective on results…
Meeting News CoveragePerspective

CONTROL-HTN: Mechanical device improved BP in patients with resistant arterial hypertension

November 21, 2014
Patients with treatment-resistant arterial hypertension had significant reductions in office-measured and ambulatory BP following arteriovenous anastomosis with a…
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CME
Experts Take: Dialogue on HTG

Experts’ Take: Dialogue on Hypertriglyceridemia

This activity is supported by an independent educational grant from Amarin Pharma Inc.

Lead by genetic studies, recent data describe a causal role of triglycerides (TG) in the formation of atherosclerosis…
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Meeting News Coverage Video
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New data may yield a 'change in the paradigm' of HF therapy

November 18, 2014
CHICAGO — Further analyses of the PARADIGM-HF trial provide more information on the efficacy of an…
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CME
Managing Acute Ischemic Stroke in the Emergency Department: Two Decades of Progress

Managing Acute Ischemic Stroke in the Emergency Department: Two Decades of Progress

This activity is supported by an educational grant from Genentech.

According to the American Heart Association Heart Disease and Stroke Statistics 2013 Update, approximately 795,000…
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