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VIDEO: Roxana Mehran, MD, discusses REGULATE-PCI results

March 31, 2015

SAN DIEGO — In this video, Roxana Mehran, MD, professor of medicine at Icahn School of Medicine at Mount Sinai and associate medical editor of Cardiology Today's Intervention, highlights results from the REGULATE-PCI study, which she presented at the American College of Cardiology Scientific Sessions.

The trial compared REG1 (Regado Biosciences), a novel anticoagulation system combining pegnivacogin and the reversal agent anivamersen, with bivalirudin among patients undergoing angioplasty. Mehran noted that while the goal was to enroll 13,200 patients, the trial was terminated upon enrollment of approximately 3,200 patients after 10 participants assigned to the REG1 group experienced severe allergic reactions compared with one participant assigned bivalirudin.

BioMed Central retracts 43 articles that used fabricated reviewers

March 31, 2015
Following an investigation which revealed attempts to manipulate the peer review process, medical and scientific publisher BioMed Central has retracted 43 articles that…
Stephen J. Nicholls, MBBS, PhD In the Journals

High-dose statins mitigate association between elevated phospholipids, MACE in patients with stable CAD

March 31, 2015
Elevated oxidized phospholipids on apolipoprotein B-100 predicted secondary major adverse CV events in patients with stable CAD, but the risk was mitigated in those…
In the Journals

Vitamin D supplementation fails to lower BP

March 31, 2015
Vitamin D does not appear to be effective as a means of lowering BP, either in individual patients or as a population-level intervention, according to recent…
Monika Sanghavi, MD In the Journals

Number of births may affect atherosclerosis risk in women

March 31, 2015
The number of live births is associated with subclinical coronary and aortic atherosclerosis in women, according to new data from the Dallas Heart Study.Researchers…
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CME
Best of Lipid Forum III

Best of Lipid Forum III

This activity is supported by an educational grant from Amgen, Inc.

Appropriate therapies for various dyslipidemias remain a challenge for practitioners struggling to reduce residual risk…
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Meeting News Coverage Video
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VIDEO: Results from three trials suggest 'significant progress' for TAVR technology

March 30, 2015
SAN DIEGO — In this video, Steven R. Bailey, MD, chief of cardiology at the University of Texas Health Sciences…
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CME
Obesity Consults: Volume 2, Number 1

Obesity Consults: Volume 2, Number 1

This activity is supported by an educational grant from Vivus, Inc.

Obesity is suboptimally managed in clinical practice despite the availability of relevantguidelines and evidence-based…
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