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Chapter 4: Ear, Nose, and Throat Manifestations of GERD

From Extraesophageal Manifestations of GERD

Laryngopharyngeal reflux (LPR) is the term used for the effects of reflux of stomach contents on the structures of the upper aerodigestive tract. The diagnosis and treatment of LPR has had a significant impact on the practice of otolaryngology.

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Question 12: How Do I Know When A Patient Receiving An Oral Antiviral Agent Has Developed Resistance And What Do I Do When This Happens?

From Curbside Consultation of the Liver: 49 Clinical Questions

Resistance is the major limitation when utilizing an oral antiviral agent for the treatment of chronic hepatitis B virus (HBV). Although it is commonly believed that resistant mutations develop in response to treatment with antiviral agents, the great majority of mutations that convey resistance to…

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Chapter 26: Functional Brain Imaging in GI Neurophysiology

From GI Motility Testing: A Laboratory and Office Handbook

Abnormal sensory processing appears to play a key role in generation of symptoms in disorders such as noncardiac chest pain, functional dyspepsia, and irritable bowel syndrome (IBS) for which symptoms may in part be due to visceral hypersensitivity.1 Distension causes pain or discomfort at lower…

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Chapter 3: Barrier Function And Theimmune Response

From Probiotics: A Clinical Guide

The ability of the intestinal tract to act as a barrier between the external environment and the closely regulated internal milieu is absolutely essential for human health. In our evolution as vertebrates, we have developed elegant mechanisms to coexist with bacteria. Colonization of the intestine with…

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Question 47: What Is The Best Approach To The Patient With Suspected Sphincter Of Oddi Dysfunction?

From Curbside Consultation of the Pancreas: 49 Clinical Questions

The single most important aspect of treating a patient suspected of having sphincter of Oddi dysfunction (SOD) is to be certain of the diagnosis. There are 3 types of SOD (Table 47-1). Although the sphincter may be found to be hypertensive in these patients on manometry, differences in the clinical…

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Chapter 6: Infections In IBD - Clostridium difficile and Cytomegalovirus

From Clinical Challenges and Complications of IBD

Inflammatory bowel diseases (IBDs), comprising Crohn’s disease (CD) and ulcerative colitis (UC), are lifelong immunologically mediated disorders affecting the gastrointestinal tract. With an onset often during young adulthood, IBD has a relapsing-remitting course. The majority of relapses relate…

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Chapter 26: Medical Management of Severe Ulcerative Colitis

From Ulcerative Colitis: The Complete Guide to Medical Management

The majority of patients with ulcerative colitis (UC) are managed with oral or topical 5-aminosalicylates and corticosteroids and do not require hospitalization. Patients who have extensive mucosal inflammation on colonoscopy and persistent symptoms of diarrhea and bleeding

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