Controversies in Hepatology: The Experts Analyze Both Sides
The field of hepatology is full of controversies and clinical dilemmas. Each day, gastroenterologists and hepatologists are faced with the challenge of making the best evidence-based decision in challenging cases that do not readily lend themselves to an easy answer, even with todays available medical literature.
Controversies in Hepatology: The Experts Analyze Both Sides is based on the principle of an academic debate. Dr. Donald Jensen is joined by 50 colleagues who present evidence-based arguments for and against 17 key controversial areas in hepatology. Each point-counterpoint is then followed up by a summarization of key points by a leading expert in that topic area.
Some Chapter Topics Include:
- Should living donor liver transplantation be considered in adult acute liver failure?
- Should hepatitis C be treated in patients with chronic kidney disease prior to kidney transplant?
- Resect or observe asymptomatic hepatic adenoma?
- Strictly adhere to the 6-month rule for recent history of alcohol abuse in potential liver transplant candidates?
- Autoimmune hepatitis: maintenance therapy for all patients or stop treatment after histologic remission?
With concise clinical information to reinforce the point-counterpoint text, Controversies in Hepatology: The Experts Analyze Both Sides will become the go-to resource for teaching and perfecting the important skills required to weigh the evidence and arrive at an outcome.
SECTION I: ACUTE LIVER DISEASE
Chapter 1: Alcoholic Hepatitis: Pentoxifylline Versus Steroids
Chapter 2: Is N-Acetylcysteine Effective in All Cases of Non-Acetaminophen Acute Liver Failure?
Chapter 3: Should Living Donor Transplantation Be Considered in Adult Acute Liver Failure
SECTION II: CHRONIC HEPATITIS B AND C
Chapter 4: Do All Patients With Chronic Hepatitis B Who Are Treatment Candidates Need an Assessment of Fibrosis?
Chapter 5: Should the Decompensated Hepatitis C Cirrhotic Be Treated With Antiviral Therapy?
Chapter 6: Should Hepatitis C Be Treated in Patients With Chronic Kidney Disease Prior to Kidney Transplant?
Chapter 7: Retransplantation for Severe Recurrent Hepatitis C Virus and Previously Failed Pegylated-Interferon/Ribavirin Therapy
Chapter 8: Does a Sustained Virologic Response at Week 72 Indicate a Cure in Chronic Hepatitis C Virus?
SECTION III: LIVER TUMORS
Chapter 9: Should Living Donor Liver Transplantation Be an Option for Patients With Hepatocellular Carcinoma Beyond the Milan Criteria?
Chapter 10: Resect or Observe Asymptomatic Hepatic Adenoma?
SECTION IV: OTHER CHRONIC LIVER DISEASES AND CIRRHOSIS
Chapter 11: Strictly Adhere to the "6-Month Rule" for Recent History of Alcohol Abuse in Potential Liver Transplant Candidates?
Chapter 12: Should Liver Biopsy Be Performed in All Patients With Nonalcoholic Fatty Liver Disease?
Chapter 13: Should the Hepatic Venous Pressure Gradient Be Sequentially Measured to Monitor Beta-Blocker Therapy in the Prophylaxis of Variceal Hemorrhage?
Chapter 14: Standard Dose or Avoid Ursodiol Therapy in Primary Sclerosing Cholangitis?
Chapter 15: Annual Screening of Primary Sclerosing Cholangitis Patients for Cholangiocarcinoma With Magnetic Resonance Cholangiopancreatography and CA 19-9?
Chapter 16: Lactulose or Rifaximin as First-Line Therapy for Hepatic Encephalopathy?
Chapter 17: Autoimmune Hepatitis: Maintenance Therapy for All Patients or Stop Treatment After Histologic Remission?
“It would be a welcome addition to gastroenterology and hepatology training program libraries and in particular fellows in training would be well served to read the point/counterpoint arguments to gain a historical perspective on the dilemmas presented here as well as take advantage of the extensive bibliographies that nicely chronicle the evolution of these disorders. One noted strength throughout the book us the extensive discussion highlighting important research gaps in areas including, but not limited to cholangiocarcinoma surveillance, first-line therapy for hepatic encephalopathy, and the sobriety period before transplantation for alcoholic cirrhosis. All gastroenterologists and hepatologists, and, in particular, fellows in training, who provide outpatient and inpatient care for hepatology patients should have this resource in their library.”
-Paul Y. Kwo, Indiana University School of Medicine, Gastroenterology
About the Editor
Donald M. Jensen, MD is Professor of Medicine, and Director of the Center for Liver Diseases, at the University of Chicago Medical Center. Dr. Jensen received his undergraduate (BS) and medical (MD) degrees from the University of Illinois in Urbana and Chicago, respectively. He completed a medicine internship and residency at Rush-Presbyterian-St. Luke’s Medical Center in Chicago where he also served as Chief Medical Resident. After completing one year of gastroenterology fellowship at Rush, Dr. Jensen went to King’s College Hospital in London, U.K., for a liver research fellowship under the mentorship of Professor Roger Williams. Returning to Chicago, Dr Jensen became a member of the Section of Digestive Diseases at Rush, specializing in clinical hepatology. In 1992, he became the Director, of the Section of Hepatology at Rush, and in 1999 the Richard B. Capps Professor of Medicine. In 2005, Dr. Jensen accepted his current position at the University of Chicago. He is board certified in both internal medicine and gastroenterology.
Dr. Jensen’s research interest is in newer treatment strategies and therapies for hepatitis C. His clinical interests are broad and include: viral hepatitis, cirrhosis, autoimmune hepatitis and hepatocellular carcinoma, among others. He has authored or co-authored 74 peer-reviewed articles, 18 invited reviews/editorials, 23 book chapters, and 2 books (in preparation). He is a member of three editorial boards. He has been a member of the national board of directors of the American Liver Foundation (ALF); president of the Illinois chapter of the ALF; and is currently Treasurer and Governing Board member of the American Association for the Study of Liver Diseases (AASLD).
Dr. Jensen has received numerous teaching awards, including Teacher of Year on three occasions at both Rush University and the University of Chicago, as well as Physician of the Year award on two occasions from the ALF. He has been named Top Doctor by Chicago Magazine for the past 12 years, and is listed in Who’s Who in the World. Dr. Jensen’s hobbies include competitive running, swimming, and cycling and he has competed in 6 marathons, 12 triathlons and one Half Ironman triathlon. He is married to Dr. Donna Hanlon and they have two children, Colin and Emily.