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Blood lead levels linked with IgE sensitization to dust mites, arthropods

November 25, 2014

A positive relationship existed between blood lead levels and total IgE levels in US adults, with high blood lead levels significantly increasing the risk for IgE sensitization to dust mites and arthropods, according to study results.

Researchers studied data from the 2005-2006 National Health and Nutrition Examination Survey and included 4,287 adults aged 20 years and older who had completed a panel of allergen-specific IgE tests and had blood lead measurements. The ImmunoCAP System (Pharmacia Diagnostics) measured total and allergen-specific IgE levels against 19 allergens, categorized as: molds, dust mites, plants, pets, arthropods, rodents and food.

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Exposure to air pollutants may augment response to allergens

November 9, 2014
ATLANTA — In this video, David B. Peden, MD, MS, Andrews Distinguished Professor of Pediatrics, The University of North Carolina at Chapel Hill, discusses his…
Meeting News Coverage

Flour, cleaning products top causes of occupational asthma in France

September 10, 2014
Flour and cleaning products were the main causes of occupational asthma in France, according to presenters at the European Respiratory Society International Congress in…
S. Nicole Chadha, MD In the Journals

Age associated with sensitivity type in pediatric patients with EoE

August 27, 2014
Aeroallergen sensitivity increased with age while food sensitivity decreased in pediatric patients with eosinophilic esophagitis, according to recent study results.S

YKL-40 levels much lower in children with severe asthma than in adults

July 11, 2014
Unlike adults, children with severe asthma did not have an association with elevated chitinase-like protein YKL-40 levels, according to recent study…
Meeting News Coverage

Researchers identify new allergen from short ragweed pollen

June 10, 2014
Investigators have identified a new allergen from short ragweed pollen that holds major diagnostic and therapeutic interest, according to research…
Meeting News Coverage

‘Trapped’ allergy campaign kicks off EAACI annual congress

June 6, 2014
The European Academy of Allergy and Clinical Immunology and Asthma-Allergy Denmark have launched a campaign emphasizing that Europeans feel…

Polyclonal cytokine profiles differentiated asthma phenotypes

May 13, 2014
Young adults with allergic asthma demonstrated a TH2-polarized cytokine response after polyclonal stimulation, suggesting that allergic and…
In the Journals

Allergens induced differential T-cell activation in patch tests

May 8, 2014
Allergens may induce differential T-cell activation in reactive tests, recently published data suggest.“This study is the first to perform…
In the Journals

Allerdictor scans genomic data, identifies allergens in 6 minutes

May 5, 2014
Researchers have developed a new artificial intelligence software system designed to predict potential allergens from broad genomic data, according…
In the Journals

New 3-D model of human respiratory tract may help clinical research

April 30, 2014
Researchers in the United Kingdom have developed an immunocompetent 3-D model of the human airway epithelium that can be used for clinical studies…
In the Journals

Vitamin D–binding genotype provided asthma protection

April 30, 2014
Researchers have identified a vitamin D–binding genotype that is protective against the development of asthma among inner-city Hispanic…
In the Journals

Asthma morbidity linked to higher urinary dichlorophenol levels

April 23, 2014
Asthma morbidity in patients with atopy and a history of wheezing is associated with high urinary dichlorophenol levels which are also associated…
In the Journals

Filaggrin expression in chronic idiopathic urticaria linked to severity of condition

April 22, 2014
Filaggrin expression might be a novel biomarker for chronic idiopathic urticaria severity; and altered filaggrin expression has physiologic effects…
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