Allergic Disease Mechanisms

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Novel SNPs identified for bone mineral accretion in children

June 24, 2015

Two novel tubulin pathway single nucleotide polymorphisms were associated with independent interactive effects of cumulative corticosteroid dose on bone mineral accretion in children with asthma who underwent various oral prednisone bursts, according to study results.

Significant decreases in bone mineral accretion occur with long-term intermittent oral corticosteroid use in children with asthma. Heung-Woo Park, MD, PhD, of the Channing Division of Network Medicine and the division of pulmonary and critical care medicine at Brigham and Women’s Hospital and Harvard Medical School, and colleagues sought to identify possible genetic factors that influence oral corticosteroid dose effects on bone mineral accretion in children with asthma.

In the Journals

Algorithm for CRS classification may predict recurrence risk, refractoriness

June 23, 2015
A diagnostic algorithm for classifying chronic rhinosinusitis demonstrated utility in determining refractoriness and recurrence risk for the condition, according to…
In the Journals

Urbanization affects development of allergen sensitization among elderly

April 13, 2015
Urbanization was linked with self-reported rhinitis symptoms and sensitization to inhalant allergens in an elderly South Korean population, according to study…
In the Journals

Breast-feeding does not affect allergy sensitization in children

April 10, 2015
The time a mother spends breast-feeding her child has no impact on the development of allergy sensitization in children at high risk for developing allergies, according…
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Exposure to air pollutants may augment response to allergens

November 9, 2014
ATLANTA — In this video, David B. Peden, MD, MS, Andrews Distinguished Professor of Pediatrics, The University…
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In the Journals

Clothing fabrics impact transfer of house dust mites

February 17, 2015
The type of clothing fabric a person wears contributed to the transfer of house dust mites from one location to another, according to study…
In the Journals

Influenza vaccine found safe in children with egg allergy

February 17, 2015
Live-attenuated influenza vaccine appeared to be safe for use in children with egg allergy and well tolerated in children with asthma, according to…
In the Journals

Influenza vaccine found safe in children with egg allergy

February 17, 2015
Live-attenuated influenza vaccine appeared to be safe for use in children with egg allergy and well tolerated in children with asthma, according to…
Industry News

Minnesota climate change may increase allergies, Lyme disease

February 16, 2015
Climatic change may lead to increases in allergies, Lyme disease and other airborne and bacterial diseases, according to a
Industry News

Actavis launches generic for AstraZeneca's Pulmicort Respules

February 16, 2015
Actavis has launched its generic version of AstraZeneca’s Pulmicort Respules after a U.S. District Court judge in New Jersey denied…
Alessandro Fiocchi In the Journals

Guidelines describe use of probiotics in preventing allergic diseases

February 4, 2015
The World Allergy Organization has released conditional guidelines for the use of probiotics during pregnancy, breast-feeding and infancy to prevent…
Giovanni Passalacqua In the Journals

More data needed on connection between vitamin D, allergies

January 6, 2015
There is insufficient evidence to indicate vitamin D supplementation helps prevent or treat certain allergic diseases in children and adolescents…
In the Journals

Diesel exhaust particle exposure increases risk of aeroallergen sensitization in high risk children

December 16, 2014
Researchers found diesel exhaust particle exposure in early childhood enhances aeroallergen sensitization and that allergic rhinitis in 4-year-old…
In the Journals

Measurable aeroallergens found in dust from high-efficiency furnace filters

November 26, 2014
Significant levels of aeroallergens were measured in dust collected from high-efficiency furnace filters in the Midwest, according to recent study…
In the Journals

Blood lead levels linked with IgE sensitization to dust mites, arthropods

November 25, 2014
A positive relationship existed between blood lead levels and total IgE levels in US adults, with high blood lead levels significantly increasing the…
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