Allergic Disease Mechanisms

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Skin patch for peanut allergy yields higher immunity in children

December 22, 2016

Children were able to overcome allergic response to peanuts by wearing a skin patch that administered epicutaneous immunotherapy in the form of peanut protein, according to clinical trial findings published in the Journal of Allergy and Clinical Immunology.

“To avoid potentially life-threatening allergic reactions, people with peanut allergy must be vigilant about the foods they eat and the environments they enter, which can be very stressful,” National Institute of Allergy and Infectious Diseases director Anthony S. Fauci, MD, said in a press release. “One goal of experimental approaches such as epicutaneous immunotherapy is to reduce this burden by training the immune system to tolerate enough peanut to protect against accidental ingestion or exposure.”

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In the Journals

Skin patch for peanut allergy yields higher immunity in children

December 22, 2016
Children were able to overcome allergic response to peanuts by wearing a skin patch that administered epicutaneous immunotherapy in the form of…

In the JournalsPerspective

Infants’ peanut consumption found safe for future growth, nutrition

July 6, 2016
Recent data suggested that early-life peanut consumption, as part of a strategy that reduces peanut allergy risk, was nutritionally safe and did not…

In the Journals

Quilizumab appears tolerable, reduces serum IgE levels

April 25, 2016
Patients in this study who received quilizumab had reduced serum immunoglobulin E levels and appeared to tolerate the humanized IgG1 monoclonal…

In the Journals

Novel IRF2BP2 mutation linked to CVID–like immunodeficiency

April 15, 2016
Researchers identified a novel mutation in IRF2BP2 in a family with a history of common variable immunodeficiency disorder, which may be the cause of…

In the Journals

Inflammatory endotypes help to identify chronic rhinosinusitis

April 12, 2016
Researchers in this study identified correlations between phenotypes and inflammatory endotypes in patients with chronic rhinosinusitis which may aid…

In the Journals

Similar patterns in Vβ TCR seen in healthy, atopic children

April 4, 2016
Researchers in this study found a similar pattern of V segments in the beta chain of T-cell regulators among atopic and healthy patients, according…

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Genetic link to cow's milk allergy may predict later allergic onset

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Researchers have identified two single nucleotide polymorphisms associated with cow’s milk allergy in pediatric patients that may pave the way…

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Patients in Cameroon show high sensitization to aeroallergens

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A significant proportion of patients in Cameroon showed a sensitization to aeroallergens, including dust mites and cockroaches, according to recent…

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IgE observed in just half of UK children with food hypersensitivity

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Researchers found immunoglobulin E-mediated food allergy in just half of observed children in a recent population based birth cohort study. Further…

In the Journals

Handbook improves parental knowledge of child’s food allergy

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Parents of pediatric patients with food allergies who received a food allergy handbook showed better knowledge, confidence and quality of life in…

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