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MondoA protein presents potential new avenue for preventing type 2 diabetes

August 27, 2016

Blocking a cellular glucose sensor in muscle improves insulin responsiveness and provides a potential target for drugs to prevent type 2 diabetes, according to researchers.

“Our new study shows that a protein called MondoA may serve as a key link between insulin resistance and accumulation of fat in muscle, which occurs in obesity-related diabetes,” Daniel P. Kelly, MD, professor and director of Center for Metabolic Origins of Disease at Sanford Burnham Prebys Medical Discovery Institute, said in a press release. “This study is the first step towards testing MondoA-targeted drugs to prevent type 2 diabetes in preclinical studies.”

AstraZeneca enters agreement with Pfizer over antibiotics portfolio

August 27, 2016
AstraZeneca announced it will sell the full commercialization and development rights of its late-stage small molecule antibiotics business to Pfizer, while AstraZeneca…

Vanderbilt-Ingram Cancer Center selects director for early detection, prevention initiative

August 27, 2016
Pierre Massion , MD, professor of cancer research and co-leader of Vanderbilt-Ingram Cancer Center’s cancer health outcomes and control program…
In the Journals

Older age associated with DVT in patients with isolated calcaneal fractures

August 27, 2016
Recently published results showed patients with isolated calcaneal fractures had an incidence of preoperative deep vein thrombosis that was almost twice as high as any…

NHLBI working group identifies knowledge gaps on role of microbiota in BP regulation

August 27, 2016
The NHLBI announced that it convened a working group to share current scientific knowledge on the role of microbiota in the regulation of BP. The working group…
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CME

Practical Lipidology®: Volume 3, Number 1

This activity is supported by an educational grant from Amgen

The reduction of low-density lipoprotein-cholesterol (LDL-C) is recognized as the primary strategy for decreasing…
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Clinical Science

Objective Quantification of Retinal Shortening: Sonographic Evidence of Intraretinal Proliferative Vitreoretinopathy

Ophthalmic Surgery, Lasers and Imaging Retina, August 2016, Volume 47 Issue 8
To evaluate retinal shortening with ultrasound (USG) in patients with retinal detachment (RD). This was a pilot…
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VIDEO: Traumatic cataract, zonular loss managed with femtosecond surgery

August 18, 2016
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