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FDA grants accelerated approval to brigatinib for ALK–positive NSCLC

April 28, 2017

The FDA granted accelerated approval to brigatinib for the treatment of patients with metastatic anaplastic lymphoma kinase–positive non–small cell lung cancer who progressed on or are intolerant to crizotinib.

The FDA recommended a dose of 90 mg orally once daily for the first 7 days. After that, if tolerated, the dose can be increased to 180 mg orally once daily.

FDA News

FDA approves Tymlos for postmenopausal women with osteoporosis

April 28, 2017
The FDA today approved an abaloparatide injection for the treatment of postmenopausal women with osteoporosis at high risk for fracture, according to a press release…
In the Journals

Pigmented lesion assay improves biopsy specificity in diagnosing melanoma

April 28, 2017
The use of a noninvasive pigmented lesion assay significantly improved biopsy specifity, which may allow dermatologists to miss fewer melanomas while reducing the number…
Meeting News

Speaker: Drug development for lupus presents opportunity, reason for optimism

April 28, 2017
DESTIN, Fla. — Despite the challenges of drug development for the treatment of systemic lupus erythematosus, there are reasons for optimism about the future…
In the Journals

Study identifies risk factors for steroid-induced hypertension after PRK

April 28, 2017
Male sex, high myopia, higher central corneal thickness, lower K value, corneal haze, type of steroid used and length of therapy were associated with a higher risk of…
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CME

Age Matters: Implementing New Recommendations for HPV Immunization in Adolescents

This activity is supported by an educational grant from Merck & Co., Inc.

Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States, as well as…
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Feature Article

Concordance of Patient and Physician Perceptions of Care in an Orthopedic Clinic

Orthopedics
Online Advanced Release, April 24, 2017
It is essential to study whether physicians' perceptions align with their patients' views, as understanding patient…
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International Liver Congress

International Liver Congress

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Meeting News

VIDEO: Hospitalization outcomes in older adults improving

April 28, 2017
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