Top Story

Epclusa shows manageable drug interaction profile with antiretrovirals

Epclusa shows manageable drug interaction profile with antiretrovirals
August 23, 2016

Epclusa showed a manageable drug interaction profile with commonly used antiretrovirals in treating patients co-infected with chronic HCV and HIV, according to a phase 1 trial.

“Overall, [sofosbuvir/velpatasvir (Epclusa, Gilead)] did not have clinically relevant drug interactions with the majority of antiretroviral regimens evaluated,” Annie Luetkemeyer, MD, associate professor at University of California San Francisco School of Medicine, told Healio.com/Hepatology. “Sofosbuvir/velpatasvir has a well characterized and manageable drug interaction profile with commonly used antiretroviral regimens.”

In the Journals

Childhood abuse increases risk for premature mortality in women

August 23, 2016
Childhood abuse was associated with greater risk for all-cause mortality in adulthood among women but not men, according to recent findings. “A large literature…
FDA News

FDA grants priority review to rucaparib for advanced BRCA–mutated ovarian cancer

August 23, 2016
The FDA granted priority review to rucaparib for the treatment of advanced ovarian cancer in patients with germline or somatic BRCA–mutated tumors. The…

PCPs should be aware of potential psoriasis risks, treatment options

August 23, 2016
Psoriasis can be visually, physically, and emotionally jarring for those with the disease. According to the National Psoriasis Foundation, approximately 7.5 million…
In the JournalsFrom OSN APAO

Application of whole blood before staining improves outcomes of macular hole surgery

August 23, 2016
Application of whole blood followed by brilliant blue staining of the internal limiting membrane allowed earlier and better visual rehabilitation in macular hole surgery…
More News Headlines »
CNE

Journal of Psychosocial Nursing and Mental Health Services July 2016 CNE Activity

This activity is co-provided by Villanova University College of Nursing and SLACK Incorporated.

Topics include psychiatric inpatient bedside handoff, advocating for the use of pharmacogenomics testing, and…
More »
Feature Article

Intraoperative Hypothermia During Surgical Fixation of Hip Fractures

Orthopedics
Online Advanced Release, August 18, 2016
Hip fractures are common orthopedic injuries and are associated with significant morbidity/mortality. Intraoperative…
More »
Featured
Zika Resource Center

Zika Resource Center

Video
Meeting News Coverage

VIDEO: Four steps to better cataract surgery

August 22, 2016
More »