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Bivalirudin compares favorably to heparin, GPIs in patients with diabetes undergoing PCI

August 28, 2015

Treatment with bivalirudin yielded similar 30-day ischemic outcomes vs. heparin and glycoprotein inhibitors, with significantly lower rates of major and minor bleeding and 1-year mortality among patients with diabetes undergoing PCI, according to recent findings.

In a meta-analysis of randomized trials, researchers evaluated four randomized controlled trials comparing bivalirudin with unfractionated heparin and glycoprotein IIb/IIIa inhibitors (GPIs) in patients with diabetes undergoing PCI (n = 5,137). They assessed the incidence of major adverse cardiac events, all-cause mortality, MI, urgent revascularization and major and minor bleeding at 30 days, as well as all-cause mortality at 1 year.

Timothy J. Ley, MD In the Journals

Persistent mutations may predict EFS, OS outcomes in AML

August 28, 2015
Persistent leukemia-associated mutations in at least 5% of bone marrow cells in day 30 remission samples appeared to significantly increase the risk for relapse and…
photo of gregory phillips In the Journals

HIV testing rates low for gay male adolescents

August 28, 2015
Gay and bisexual teenage boys were unlikely to undergo HIV testing, according to research published in the Journal of Adolescent Health. “As one of the first…
In the Journals

Age, gender, subtype may influence recurrence of AMD after anti-VEGF treatment

August 28, 2015
Recurrence of neovascular age-related macular degeneration after anti-VEGF treatment may be associated with age and gender, and occur sooner in patients with polypoidal…

AMA task force emphasizes importance of prescription drug monitoring programs

August 28, 2015
The American Medical Association Task Force to Reduce Opioid Abuse recently announced the first of several recommendations to address the growing opioid epidemic…
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Infectious Disease Case Consults

The Patient with Conjunctivitis

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This CME activity will focus on the diagnosis and management of patients with conjunctivitis.
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Feature Article

Ultrasound for Infants at Risk for Developmental Dysplasia of the Hip

Orthopedics, August 2015, Volume 38 Issue 8
The best screening method for developmental dysplasia of the hip is controversial. Ultrasonography is sensitive, but…
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Meeting News Coverage Video
VIDEO: Anastrozole 'an option' for women with ductal carcinoma in situ

VIDEO: Anastrozole 'an option' for women with ductal carcinoma in situ

August 21, 2015
CHICAGO — The aromatase inhibitor anastrozole may serve as a potential treatment option for women with ductal…
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