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Trastuzumab plus adjuvant chemotherapy improved OS DFS in HER 2 positive breast cancer

November 21, 2014

The addition of trastuzumab to adjuvant chemotherapy conferred “substantial and durable improvement in survival” among women with early-stage, HER-2–positive breast cancer, according to a joint analysis of long-term results from randomized two trials.

“This study reflects that excellent science in collaboration between NCI-sponsored cancer cooperative groups and our patients can clearly help improve standards of care,” Edith A. Perez, MD, director of the breast cancer program at Mayo Clinic in Jacksonville, Fla., and a HemOnc Today Editorial Board member, told HemOnc Today. “Some specifics included a very low rate of local recurrence and serious cardiac side effects, even though all patients received anthracyclines prior to paclitaxel–trastuzumab. This regimen is a well-established standard of care regimen for eligible patients.”

In the Journals

EPA with statins may reduce periprocedural MI in PCI

November 21, 2014
Patients receiving eicosapentaenoic acid with statins before PCI experienced reduced type IVa MI compared with those receiving statins only, recent findings…

Apellis to acquire Potentia Pharmaceuticals

November 21, 2014
Apellis Pharmaceuticals has entered into an agreement to acquire Potentia Pharmaceuticals, according to a press release.Through the agreement, Apellis obtained the…
In the Journals

Lung transplant increased risk for dysglycemia, new-onset diabetes

November 21, 2014
In the first year after undergoing a lung transplant, most patients experience dysglycemia and may also be at significant risk for new-onset diabetes, according to…
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In Focus: Advances in AMD – Clinical Case: Starting therapy in a patient newly diagnosed with wet AMD

This activity is supported by an educational grant from Genentech, Inc.

Successful early treatment of wet age-related macular degeneration offers the best odds for maintaining visual acuity…
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Major Article

Research Education: Findings of a Study of Teaching–Learning Research Using Multiple Analytical Perspectives

Journal of Nursing Education
Online Advanced Release, November 20, 2014
This multimethod, qualitative study provides results for educators of nursing doctoral students to consider. Combining…
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Meeting News Coverage Video
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VIDEO: Satellite-based ECG system may improve outcomes for patients with STEMI

November 21, 2014
CHICAGO — Srihari S. Naidu, MD, director of the cardiac catheterization lab at Winthrow University Hospital in…
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