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Potential drug decreased viral load in patients with various HCV genotypes

October 23, 2014

Interim results from an ongoing clinical trial revealed that a microRNA therapeutic was well-tolerated and safe for the treatment of hepatitis C virus infection, according to a company release from Regulus Therapeutics.

In the trial, currently taking place in the Netherlands, RG-101 (Regulus Therapeutics), a GalNac-conjugated anti-miR targeting microRNA-122, was dosed at 2 mg/kg and given to 14 patients with HCV and various genotypes. This treatment resulted in significant and sustained reductions in HCV RNA among the patients, including those with difficult to treat genotypes and experienced viral relapse after a prior interferon-based regimen, according to the release.

Meeting News Coverage

Poor neurologic recovery rates seen in acetabular fracture patients with iatrogenic injuries

October 23, 2014
TAMPA, Fla. — In a retrospective review, researchers found a third of patients with documented neurologic injuries who underwent surgery for acetabular fractures…
figure Meeting News Coverage

Physical, social development common reasons for breastfeeding beyond 1 year

October 23, 2014
SAN DIEGO — Physical and social development are considered most important among mothers who choose to breast-feed their child beyond 1 year of age, according to…
Perspectives on Glaucoma

Cataract surgery lowers IOP more in patients with higher pre-op IOP

October 23, 2014
Patients with chronic angle-closure glaucoma and narrow angles may benefit greatly from cataract surgery, according to a study recently published in the Journal of
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Regimen Selection in HIV: Considering New Options to Optimize Outcomes

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

More than two decades into the antiretroviral therapy (ART) era, there are numerous options for HIV treatment. The goal…
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Research Briefs

Professional Socialization of Students Enrolled in an Online Doctor of Philosophy Program in Nursing

Journal of Nursing Education, October 2014, Volume 53 Issue 10
A descriptive online survey design was used to describe professional socialization of students enrolled in an online…
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Physical therapist talks emerging trends in treatment and rehabilitation of pediatric ACL injuries

October 23, 2014
NEW YORK CITY — Maureen C. Suhr, PT, talked about the emerging trends in treatment and rehabilitation of…
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